BDBM50045742 3-[3,4-Dimethyl-1-(3-thiophen-3-yl-propyl)-piperidin-4-yl]-phenol::CHEMBL317097

SMILES C[C@H]1CN(CCCc2ccsc2)CC[C@@]1(C)c1cccc(O)c1

InChI Key InChIKey=DTCRXMSIIFTNHL-OXJNMPFZSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50045742   

TargetMu-type opioid receptor(Rattus norvegicus (rat))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50045742(3-[3,4-Dimethyl-1-(3-thiophen-3-yl-propyl)-piperid...)
Affinity DataKi:  0.260nMAssay Description:Binding affinity towards mu-opioid receptor by displacement of [3H]-NAL at 10 nM from rat brain homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50045742(3-[3,4-Dimethyl-1-(3-thiophen-3-yl-propyl)-piperid...)
Affinity DataKi:  0.260nMAssay Description:Binding affinity towards mu-opioid receptor by the displacement of [3H]-Nal in rat brain homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50045742(3-[3,4-Dimethyl-1-(3-thiophen-3-yl-propyl)-piperid...)
Affinity DataKi:  10nMAssay Description:Binding affinity towards kappa-opioid receptor by displacement of [3H]-EKC at from guinea pig cortical tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50045742(3-[3,4-Dimethyl-1-(3-thiophen-3-yl-propyl)-piperid...)
Affinity DataKi:  10nMAssay Description:Binding affinity towards kappa opioid receptor by displacement of [3H]-EKC in guinea pig cortical tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed