BDBM50045924 (E)-3,5-stilbenediol::(E)-5-(2-phenylethenyl)-1,3-benzenediol::5-[(1E)-2-phenylethenyl]benzene-1,3-diol::5-[(E)-2-phenylvinyl]benzene-1,3-diol::CHEMBL101506::Stilbene, 1f::pinosylvine::trans-3,5-dihydroxystilbene::trans-pinosylvin

SMILES Oc1cc(O)cc(\C=C\c2ccccc2)c1

InChI Key InChIKey=YCVPRTHEGLPYPB-VOTSOKGWSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50045924   

TargetCytochrome P450 1B1(Homo sapiens (Human))
University Of Tokyo

LigandPNGBDBM50045924((E)-3,5-stilbenediol | (E)-5-(2-phenylethenyl)-1,3...)
Affinity DataKi:  74.3nM ΔG°:  -10.1kcal/molepH: 8.0 T: 2°CAssay Description:The ethoxyresorufin-O-deethylase (EROD) assay is used to test the activity of CYP1B1. More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50045924((E)-3,5-stilbenediol | (E)-5-(2-phenylethenyl)-1,3...)
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at human TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced increase of intracellular calcium levelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily A member 1(Rattus norvegicus)
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50045924((E)-3,5-stilbenediol | (E)-5-(2-phenylethenyl)-1,3...)
Affinity DataIC50:  1.21E+4nMAssay Description:Agonist activity at rat TRPA1 expressed in HEK293 cells assessed as induction of intracellular calcium levelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50045924((E)-3,5-stilbenediol | (E)-5-(2-phenylethenyl)-1,3...)
Affinity DataIC50:  1.93E+5nMAssay Description:Tested in vitro for the inhibition of protein-tyrosine kinase p56lck using angiotensin I (1.2 mM) and [gamma-32P]-ATP (50 pM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed