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BDBM50045995 CHEMBL100641::[4-(3-Hydroxy-3,3-diphenyl-propionyl)-piperazin-1-yl]-(2-methyl-pyridin-3-yl)-acetonitrile

SMILES: Cc1ncccc1C(C#N)N1CCN(CC1)C(=O)CC(O)(c1ccccc1)c1ccccc1

InChI Key: InChIKey=XEWGFOJEIKKSMQ-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50045995   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Platelet activating factor receptor


(Cavia porcellus)
BDBM50045995
PNG
(CHEMBL100641 | [4-(3-Hydroxy-3,3-diphenyl-propiony...)
Show SMILES Cc1ncccc1C(C#N)N1CCN(CC1)C(=O)CC(O)(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C27H28N4O2/c1-21-24(13-8-14-29-21)25(20-28)30-15-17-31(18-16-30)26(32)19-27(33,22-9-4-2-5-10-22)23-11-6-3-7-12-23/h2-14,25,33H,15-19H2,1H3
MMDB

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Similars

Article
PubMed
n/an/a 17n/an/an/an/an/an/a



J. Uriach & Cía, S.A.

Curated by ChEMBL


Assay Description
Inhibition of PAF-induced platelet aggregation


J Med Chem 36: 2984-97 (1993)


Article DOI: 10.1021/jm00072a019
BindingDB Entry DOI: 10.7270/Q2ZS2VKZ
More data for this
Ligand-Target Pair