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BDBM50046003 (3-{4-[Cyano-(2-methyl-pyridin-3-yl)-methyl]-piperazin-1-yl}-3-oxo-1-phenyl-propyl)-methyl-carbamic acid methyl ester::CHEMBL100340

SMILES: COC(=O)N(C)C(CC(=O)N1CCN(CC1)C(C#N)c1cccnc1C)c1ccccc1

InChI Key: InChIKey=KCNFJCRMUHVBER-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50046003   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Platelet activating factor receptor


(Cavia porcellus)
BDBM50046003
PNG
((3-{4-[Cyano-(2-methyl-pyridin-3-yl)-methyl]-piper...)
Show SMILES COC(=O)N(C)C(CC(=O)N1CCN(CC1)C(C#N)c1cccnc1C)c1ccccc1
Show InChI InChI=1S/C24H29N5O3/c1-18-20(10-7-11-26-18)22(17-25)28-12-14-29(15-13-28)23(30)16-21(27(2)24(31)32-3)19-8-5-4-6-9-19/h4-11,21-22H,12-16H2,1-3H3
MMDB

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Similars

Article
PubMed
n/an/a 20n/an/an/an/an/an/a



J. Uriach & Cía, S.A.

Curated by ChEMBL


Assay Description
Inhibition of PAF-induced platelet aggregation


J Med Chem 36: 2984-97 (1993)


Article DOI: 10.1021/jm00072a019
BindingDB Entry DOI: 10.7270/Q2ZS2VKZ
More data for this
Ligand-Target Pair