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BDBM50046007 CHEMBL103995::[4-(3-Allylamino-3-phenyl-propionyl)-piperazin-1-yl]-(2-methyl-pyridin-3-yl)-acetonitrile

SMILES: Cc1ncccc1C(C#N)N1CCN(CC1)C(=O)CC(NCC=C)c1ccccc1

InChI Key: InChIKey=LJZTWFJYXBOVNF-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50046007   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Platelet activating factor receptor


(Cavia porcellus)
BDBM50046007
PNG
(CHEMBL103995 | [4-(3-Allylamino-3-phenyl-propionyl...)
Show SMILES Cc1ncccc1C(C#N)N1CCN(CC1)C(=O)CC(NCC=C)c1ccccc1
Show InChI InChI=1S/C24H29N5O/c1-3-11-27-22(20-8-5-4-6-9-20)17-24(30)29-15-13-28(14-16-29)23(18-25)21-10-7-12-26-19(21)2/h3-10,12,22-23,27H,1,11,13-17H2,2H3
MMDB

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Similars

Article
PubMed
n/an/a 18n/an/an/an/an/an/a



J. Uriach & Cía, S.A.

Curated by ChEMBL


Assay Description
Inhibition of PAF-induced platelet aggregation


J Med Chem 36: 2984-97 (1993)


Article DOI: 10.1021/jm00072a019
BindingDB Entry DOI: 10.7270/Q2ZS2VKZ
More data for this
Ligand-Target Pair