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BDBM50046020 (3-{4-[Cyano-(2-methyl-pyridin-3-yl)-methyl]-piperazin-1-yl}-3-oxo-1-phenyl-propyl)-carbamic acid benzyl ester::CHEMBL431049

SMILES: Cc1ncccc1C(C#N)N1CCN(CC1)C(=O)CC(NC(=O)OCc1ccccc1)c1ccccc1

InChI Key: InChIKey=GNVBBCNPKCDRQD-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50046020   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Platelet activating factor receptor


(Cavia porcellus)
BDBM50046020
PNG
((3-{4-[Cyano-(2-methyl-pyridin-3-yl)-methyl]-piper...)
Show SMILES Cc1ncccc1C(C#N)N1CCN(CC1)C(=O)CC(NC(=O)OCc1ccccc1)c1ccccc1
Show InChI InChI=1S/C29H31N5O3/c1-22-25(13-8-14-31-22)27(20-30)33-15-17-34(18-16-33)28(35)19-26(24-11-6-3-7-12-24)32-29(36)37-21-23-9-4-2-5-10-23/h2-14,26-27H,15-19,21H2,1H3,(H,32,36)
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Similars

Article
PubMed
n/an/a 22n/an/an/an/an/an/a



J. Uriach & Cía, S.A.

Curated by ChEMBL


Assay Description
Inhibition of PAF-induced platelet aggregation


J Med Chem 36: 2984-97 (1993)


Article DOI: 10.1021/jm00072a019
BindingDB Entry DOI: 10.7270/Q2ZS2VKZ
More data for this
Ligand-Target Pair