BDBM50046367 CHEMBL321322::[2-[2-(1-Formyl-4-guanidino-butylcarbamoyl)-pyrrolidin-1-yl]-1-(4-hydroxy-phenyl)-2-oxo-ethyl]-carbamic acid tert-butyl ester

SMILES [#6]C([#6])([#6])[#8]-[#6](=O)-[#7]-[#6@@H](-[#6](=O)-[#7]-1-[#6]-[#6]-[#6]-[#6@H]-1-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#6]=O)-c1ccc(-[#8])cc1

InChI Key InChIKey=QVDOSWZUBZJJCH-YTQUADARSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50046367   

TargetPlasminogen(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50046367(CHEMBL321322 | [2-[2-(1-Formyl-4-guanidino-butylca...)
Affinity DataIC50:  1.60E+4nMAssay Description:Compound was tested in vitro for inhibitory activity against t-PA (tissue plasminogen activator)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50046367(CHEMBL321322 | [2-[2-(1-Formyl-4-guanidino-butylca...)
Affinity DataIC50:  1.60E+4nMAssay Description:Inhibitory activity against plasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50046367(CHEMBL321322 | [2-[2-(1-Formyl-4-guanidino-butylca...)
Affinity DataIC50:  1.60E+4nMAssay Description:Inhibitory activity against factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50046367(CHEMBL321322 | [2-[2-(1-Formyl-4-guanidino-butylca...)
Affinity DataIC50:  1.60E+4nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50046367(CHEMBL321322 | [2-[2-(1-Formyl-4-guanidino-butylca...)
Affinity DataIC50:  1.60E+4nMAssay Description:Inhibitory activity against trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed