BDBM50046855 4-[2-(2-tert-Butoxycarbonylamino-3-cyclohexyl-propionylamino)-3-methyl-pentanoylamino]-3-hydroxy-5-(1H-indol-3-yl)-pentanoic acid::CHEMBL145539

SMILES CCC(C)[C@H](NC(=O)[C@H](CC1CCCCC1)NC(=O)OC(C)(C)C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)CC(O)=O

InChI Key InChIKey=BTJOVRIUFYIFDU-IEIUARPUSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50046855   

TargetEndothelin-converting enzyme 1(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50046855(4-[2-(2-tert-Butoxycarbonylamino-3-cyclohexyl-prop...)
Affinity DataIC50:  890nMAssay Description:Inhibition of conversion of big endothelial-1 (Big ET-1) to ET-1 by endothelin converting enzyme(ECE) in rat lung membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Bos taurus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50046855(4-[2-(2-tert-Butoxycarbonylamino-3-cyclohexyl-prop...)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of conversion of hemoglobin by commercially purchased bovine spleen cathepsin D.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed