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BDBM50047072 4-[1-(4-Bromo-benzyl)-5-chloro-1H-benzoimidazol-2-yl]-3,3-dimethyl-butyric acid::CHEMBL18093

SMILES: CC(C)(CC(O)=O)Cc1nc2cc(Cl)ccc2n1Cc1ccc(Br)cc1

InChI Key: InChIKey=BWFOQEPCUOWLLA-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50047072   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Prostanoid TP receptor


(Homo sapiens (Human))
BDBM50047072
PNG
(4-[1-(4-Bromo-benzyl)-5-chloro-1H-benzoimidazol-2-...)
Show SMILES CC(C)(CC(O)=O)Cc1nc2cc(Cl)ccc2n1Cc1ccc(Br)cc1
Show InChI InChI=1S/C20H20BrClN2O2/c1-20(2,11-19(25)26)10-18-23-16-9-15(22)7-8-17(16)24(18)12-13-3-5-14(21)6-4-13/h3-9H,10-12H2,1-2H3,(H,25,26)
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Similars

Article
PubMed
13n/an/an/an/an/an/an/an/a



Carpibem

Curated by ChEMBL


Assay Description
Tested in vitro for inhibition constant against TXA2 / PGH-2 receptor using [125I]-PTA-OH binding affinity to human platelets


J Med Chem 36: 1175-87 (1993)


Article DOI: 10.1021/jm00061a008
BindingDB Entry DOI: 10.7270/Q2R49PT8
More data for this
Ligand-Target Pair