BDBM50047097 2-{2-[4-(1H-Indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]-ethyl}-2H-naphtho[1,8-cd]isothiazole 1,1-dioxide::CHEMBL274517

SMILES O=S1(=O)N(CCN2CCC(=CC2)c2c[nH]c3ccccc23)c2cccc3cccc1c23

InChI Key InChIKey=ZSUPXNKHJARQNU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50047097   

TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Centre De Recherches De Vitry-Alfortville

Curated by ChEMBL
LigandPNGBDBM50047097(2-{2-[4-(1H-Indol-3-yl)-3,6-dihydro-2H-pyridin-1-y...)
Affinity DataIC50:  81nMAssay Description:Binding affinity at dopamine receptor D2 by the inhibition of binding to [3H]-spiperone in rat striatal membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Centre De Recherches De Vitry-Alfortville

Curated by ChEMBL
LigandPNGBDBM50047097(2-{2-[4-(1H-Indol-3-yl)-3,6-dihydro-2H-pyridin-1-y...)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of [3H]-peroxitine binding to rat cortical membranes as measure of inhibitory activity towards 5-HT uptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed