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BDBM50047191 8-[2-(2-Methoxy-phenyl)-vinyl]-1,3,7-trimethyl-3,7-dihydro-purine-2,6-dione::CHEMBL282864

SMILES: COc1ccccc1\C=C\c1nc2n(C)c(=O)n(C)c(=O)c2n1C

InChI Key: InChIKey=XCIGERFQHDEQOA-MDZDMXLPSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50047191   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Adenosine receptor A1


(Rattus norvegicus (rat))
BDBM50047191
PNG
(8-[2-(2-Methoxy-phenyl)-vinyl]-1,3,7-trimethyl-3,7...)
Show SMILES COc1ccccc1\C=C\c1nc2n(C)c(=O)n(C)c(=O)c2n1C
Show InChI InChI=1S/C17H18N4O3/c1-19-13(10-9-11-7-5-6-8-12(11)24-4)18-15-14(19)16(22)21(3)17(23)20(15)2/h5-10H,1-4H3/b10-9+
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PC sid
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Similars

Article
PubMed
4.76E+3n/an/an/an/an/an/an/an/a



National Institute of Diabetes

Curated by ChEMBL


Assay Description
Affinity against Adenosine A1 receptor in rat brain using [3H]- PIA as radioligand


J Med Chem 36: 1333-42 (1993)


Article DOI: 10.1021/jm00062a005
BindingDB Entry DOI: 10.7270/Q2BV7FPB
More data for this
Ligand-Target Pair