BDBM50048564 8-(2,2-Dimethoxy-ethyl)-3-(4-iodo-phenyl)-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid methyl ester::CHEMBL153361

SMILES COC(CN1C2CCC1C(C(C2)c1ccc(I)cc1)C(=O)OC)OC

InChI Key InChIKey=CNNOGXRSIJEFTP-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50048564   

TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Research Biochemicals International

Curated by ChEMBL
LigandPNGBDBM50048564(8-(2,2-Dimethoxy-ethyl)-3-(4-iodo-phenyl)-8-aza-bi...)
Affinity DataKi:  1.70nMAssay Description:In vitro binding affinity towards serotonin transporter in rat cerebral cortical homogenates by [3H]paroxetine displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Research Biochemicals International

Curated by ChEMBL
LigandPNGBDBM50048564(8-(2,2-Dimethoxy-ethyl)-3-(4-iodo-phenyl)-8-aza-bi...)
Affinity DataKi:  6.80nMAssay Description:In vitro binding affinity towards dopamine transporter in rat striatal membranes by [3H]GBR-12395 displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
Research Biochemicals International

Curated by ChEMBL
LigandPNGBDBM50048564(8-(2,2-Dimethoxy-ethyl)-3-(4-iodo-phenyl)-8-aza-bi...)
Affinity DataKi:  110nMAssay Description:In vitro binding affinity towards Norepinephrine transporter rat cerebral cortical homogenates by [3H]nisoxetine displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed