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BDBM50048912 CHEMBL3315210

SMILES: OC(=O)CNC(=O)Cn1ccc2cc(ccc12)-c1cnc2ccccc2c1

InChI Key: InChIKey=ISALHTCQJORZRQ-UHFFFAOYSA-N

Data: 1 EC50

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50048912   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Dopamine receptor D2L/neurotensin receptor NTS1


(Homo sapiens (Human))
BDBM50048912
PNG
(CHEMBL3315210)
Show SMILES OC(=O)CNC(=O)Cn1ccc2cc(ccc12)-c1cnc2ccccc2c1
Show InChI InChI=1S/C21H17N3O3/c25-20(23-12-21(26)27)13-24-8-7-16-9-14(5-6-19(16)24)17-10-15-3-1-2-4-18(15)22-11-17/h1-11H,12-13H2,(H,23,25)(H,26,27)
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PC cid
PC sid
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Similars

Article
PubMed
n/an/an/an/a>1.00E+5n/an/an/an/a



The Scripps Research Institute

Curated by ChEMBL


Assay Description
Agonist activity at NTSR1 (unknown origin) expressed in CHO cells assessed as potentiation of NT(8-13) peptide-induced change in intracellular Ca2+ l...


Bioorg Med Chem Lett 24: 3974-8 (2014)


Article DOI: 10.1016/j.bmcl.2014.06.033
BindingDB Entry DOI: 10.7270/Q2ZP47RG
More data for this
Ligand-Target Pair