BDBM50049577 6-[(3-Methoxy-phenylamino)-methyl]-pyrido[3,2-d]pyrimidine-2,4-diamine::CHEMBL52836

SMILES COc1cccc(NCc2ccc3nc(N)nc(N)c3n2)c1

InChI Key InChIKey=VUDSXUWVNZOREL-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50049577   

TargetDihydrofolate reductase(Rattus norvegicus (rat))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50049577(6-[(3-Methoxy-phenylamino)-methyl]-pyrido[3,2-d]py...)
Affinity DataIC50:  200nMAssay Description:Inhibitory activity against rat liver dihydrofolate reductase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50049577(6-[(3-Methoxy-phenylamino)-methyl]-pyrido[3,2-d]py...)
Affinity DataIC50:  100nMAssay Description:Inhibitory activity against Toxoplasma gondii dihydrofolate reductase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50049577(6-[(3-Methoxy-phenylamino)-methyl]-pyrido[3,2-d]py...)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of Pneumocystis carinii dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50049577(6-[(3-Methoxy-phenylamino)-methyl]-pyrido[3,2-d]py...)
Affinity DataIC50:  100nMAssay Description:Inhibition of Toxoplasma gondii dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50049577(6-[(3-Methoxy-phenylamino)-methyl]-pyrido[3,2-d]py...)
Affinity DataIC50:  200nMAssay Description:Inhibition of rat liver dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Saccharomyces cerevisiae)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50049577(6-[(3-Methoxy-phenylamino)-methyl]-pyrido[3,2-d]py...)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibitory activity against Pneumocystis carinii dihydrofolate reductase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed