BDBM50049748 (2S,4S)-2-Amino-4-(4,4-diphenyl-butyl)-pentanedioic acid::2-Amino-4-(4,4-diphenyl-butyl)-pentanedioic acid::CHEMBL39338
SMILES N[C@@H](C[C@H](CCCC(c1ccccc1)c1ccccc1)C(O)=O)C(O)=O
InChI Key InChIKey=DWLOVDOPFJPWNE-HKUYNNGSSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 24 hits for monomerid = 50049748
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
The Royal Danish School Of Pharmacy
Curated by ChEMBL
The Royal Danish School Of Pharmacy
Curated by ChEMBL
Affinity DataKi: 3.00E+4nMAssay Description:Agonist potency against cloned Metabotropic glutamate receptor 3 (mGluR-3).More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
The Royal Danish School Of Pharmacy
Curated by ChEMBL
The Royal Danish School Of Pharmacy
Curated by ChEMBL
Affinity DataKi: 5.00E+4nMAssay Description:Antagonist potency against cloned Metabotropic glutamate receptor 2More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
The Royal Danish School Of Pharmacy
Curated by ChEMBL
The Royal Danish School Of Pharmacy
Curated by ChEMBL
Affinity DataKi: >3.00E+5nMAssay Description:Agonist potency against cloned human metabotropic glutamate receptor 1More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 8(Homo sapiens (Human))
The Royal Danish School Of Pharmacy
Curated by ChEMBL
The Royal Danish School Of Pharmacy
Curated by ChEMBL
Affinity DataKi: >3.00E+5nMAssay Description:Agonist potency against cloned Metabotropic glutamate receptor 8 (mGluR-8).More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 7(Homo sapiens (Human))
The Royal Danish School Of Pharmacy
Curated by ChEMBL
The Royal Danish School Of Pharmacy
Curated by ChEMBL
Affinity DataKi: >3.00E+5nMAssay Description:Agonist potency against cloned Metabotropic glutamate receptor 7 (mGluR-7).More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
The Royal Danish School Of Pharmacy
Curated by ChEMBL
The Royal Danish School Of Pharmacy
Curated by ChEMBL
Affinity DataKi: >3.00E+5nMAssay Description:Agonist potency against cloned metabotropic glutamate receptor 5More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
The Royal Danish School Of Pharmacy
Curated by ChEMBL
The Royal Danish School Of Pharmacy
Curated by ChEMBL
Affinity DataKi: >3.00E+5nMAssay Description:Agonist potency against cloned human Metabotropic glutamate receptor 4 (mGluR-4)More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 7(Homo sapiens (Human))
The Royal Danish School Of Pharmacy
Curated by ChEMBL
The Royal Danish School Of Pharmacy
Curated by ChEMBL
Affinity DataIC50: >3.00E+5nMAssay Description:Tested for agonist activity in non-neuronal cells (RGT) expressing human mGlu7a receptor by measuring L-AP4 (1000 uM of forskolin (15 microM)-stimula...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
The Royal Danish School Of Pharmacy
Curated by ChEMBL
The Royal Danish School Of Pharmacy
Curated by ChEMBL
Affinity DataIC50: >3.00E+5nMAssay Description:Tested for agonist activity in non-neuronal cells (RGT) expressing human Metabotropic glutamate receptor 5 by measuring ACPD (100 uM)-stimulated phos...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
The Royal Danish School Of Pharmacy
Curated by ChEMBL
The Royal Danish School Of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 400nMAssay Description:Inhibitory activity of the compound against human Metabotropic glutamate receptor 2More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
The Royal Danish School Of Pharmacy
Curated by ChEMBL
The Royal Danish School Of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 3.00E+4nMAssay Description:In vitro antagonist activity at recombinant human Metabotropic glutamate receptor 3 expressed in RGT cells.More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
The Royal Danish School Of Pharmacy
Curated by ChEMBL
The Royal Danish School Of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 5.00E+4nMAssay Description:In vitro antagonist activity at recombinant human Metabotropic glutamate receptor 2 expressed in RGT cells.More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
The Royal Danish School Of Pharmacy
Curated by ChEMBL
The Royal Danish School Of Pharmacy
Curated by ChEMBL
Affinity DataIC50: >3.00E+5nMAssay Description:In vitro antagonist activity at recombinant human Metabotropic glutamate receptor 4 expressed in RGT cells.More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 8(Homo sapiens (Human))
The Royal Danish School Of Pharmacy
Curated by ChEMBL
The Royal Danish School Of Pharmacy
Curated by ChEMBL
Affinity DataIC50: >3.00E+5nMAssay Description:In vitro antagonist activity at recombinant Metabotropic glutamate receptor 8 expressed in RGT cells.More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
The Royal Danish School Of Pharmacy
Curated by ChEMBL
The Royal Danish School Of Pharmacy
Curated by ChEMBL
Affinity DataIC50: >3.00E+5nMAssay Description:In vitro antagonist activity at recombinant Metabotropic glutamate receptor 5 expressed in RGT cells.More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
The Royal Danish School Of Pharmacy
Curated by ChEMBL
The Royal Danish School Of Pharmacy
Curated by ChEMBL
Affinity DataIC50: >3.00E+5nMAssay Description:In vitro antagonist activity at recombinant human Metabotropic glutamate receptor 1 expressed in RGT cells.More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
The Royal Danish School Of Pharmacy
Curated by ChEMBL
The Royal Danish School Of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 3.00E+4nMAssay Description:Tested for agonist activity in non-neuronal cells (RGT) expressing human Metabotropic glutamate receptor 3 by measuring ACPD (3 uM) induced inhibitio...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 8(Homo sapiens (Human))
The Royal Danish School Of Pharmacy
Curated by ChEMBL
The Royal Danish School Of Pharmacy
Curated by ChEMBL
Affinity DataIC50: >3.00E+5nMAssay Description:Tested for agonist activity in non-neuronal cells (RGT) expressing human Metabotropic glutamate receptor 8 by measuring L-AP4 (0.3 uM of forskolin) (...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
The Royal Danish School Of Pharmacy
Curated by ChEMBL
The Royal Danish School Of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 5.00E+4nMAssay Description:Tested for agonist activity in non-neuronal cells (RGT) expressing human Metabotropic glutamate receptor 2 by measuring ACPD (3 uM) induced inhibitio...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
The Royal Danish School Of Pharmacy
Curated by ChEMBL
The Royal Danish School Of Pharmacy
Curated by ChEMBL
Affinity DataIC50: >3.00E+5nMAssay Description:Tested for agonist activity in non-neuronal cells (RGT) expressing human Metabotropic glutamate receptor 4 by measuring L-AP4 (3 uM) induced inhibiti...More data for this Ligand-Target Pair
Affinity DataIC50: 1.47E+5nMAssay Description:Binding affinity against Ionotropic glutamate receptor using [3H]- CGS-19755 displacement from rat forebrain preparationsMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 2(Rattus norvegicus)
Centre De Neurochimie Du Cnrs
Curated by ChEMBL
Centre De Neurochimie Du Cnrs
Curated by ChEMBL
Affinity DataIC50: 4.10E+3nMAssay Description:Compound was tested for its ability to displace metabotropic glutamate binding to rat brain membranes using [3H]glutamate radioligand.More data for this Ligand-Target Pair
Affinity DataIC50: 1.47E+5nMAssay Description:Binding affinity against Ionotropic glutamate receptor using [3H]- CGS-19755 displacement from rat forebrain preparationsMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
The Royal Danish School Of Pharmacy
Curated by ChEMBL
The Royal Danish School Of Pharmacy
Curated by ChEMBL
Affinity DataIC50: >3.00E+5nMAssay Description:Tested for agonist activity in non-neuronal cells (RGT) expressing human Metabotropic glutamate receptor 1 by measuring ACPD (100 uM)-stimulated phos...More data for this Ligand-Target Pair