BDBM50049757 ()-2-(6-Chloro-pyridin-3-yl)-7-aza-bicyclo[2.2.1]heptane::(+)-2-(6-Chloro-pyridin-3-yl)-7-aza-bicyclo[2.2.1]heptane::(+)-epibatidine::(-)-2-(6-Chloro-pyridin-3-yl)-7-aza-bicyclo[2.2.1]heptane::(1R,2R,4S)-epibatidine::(2R)-2-(6-chloropyridin-3-yl)-7-aza-bicyclo[2.2.1]heptane hydrochloride::(2R,4S)-2-(6-Chloro-pyridin-3-yl)-7-aza-bicyclo[2.2.1]heptane::(2R,4S)-2-(6-Iodo-pyridin-3-yl)-7-aza-bicyclo[2.2.1]heptane::(2R,4S)-2-(6-chloropyridin-3-yl)-7-aza-bicyclo[2.2.1]heptane::(R)-2-(6-Chloro-pyridin-3-yl)-7-aza-bicyclo[2.2.1]heptane::(R)-2-(6-Chloro-pyridin-3-yl)-7-methyl-7-aza-bicyclo[2.2.1]heptane::2-(6-Chloro-pyridin-3-yl)-5-methyl-7-aza-bicyclo[2.2.1]heptane::2-(6-Chloro-pyridin-3-yl)-7-aza-bicyclo[2.2.1]heptane::2-(6-Chloro-pyridin-3-yl)-7-aza-bicyclo[2.2.1]heptane (epibatidine)::2-(6-Chloro-pyridin-3-yl)-7-aza-bicyclo[2.2.1]heptane(+/-) epibatidine::2-(6-Chloro-pyridin-3-yl)-7-aza-bicyclo[2.2.1]heptane(Epibatidine)::2-(6-Chloro-pyridin-3-yl)-7-azonia-bicyclo[2.2.1]heptane::2-(6-chloropyridin-3-yl)-7-aza-bicyclo[2.2.1]heptane::2-Pyridin-3-yl-7-aza-bicyclo[2.2.1]heptane::CHEMBL6623::EPIBATIDINE::Epibatidine, (+/-)::Epibatidine-(+)::Epibatidine-(-)::exo-2-(6-chloropyridin-3-yl)-7-aza-bicyclo[2.2.1]heptane::rac-(2R)-2-(6-chloropyridin-3-yl)-7-aza-bicyclo[2.2.1]heptane

SMILES: c1cc(ncc1[C@H]2C[C@@H]3CC[C@H]2N3)Cl

InChI Key: InChIKey=NLPRAJRHRHZCQQ-UHFFFAOYSA-N

Data: 200 KI  6 IC50  11 Kd  28 EC50

PDB links: 14 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 245 hits for monomerid = 50049757   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuronal acetylcholine receptor subunit alpha-4/beta-2 (Human)	BDBM50049757 ((2R,4S)-2-(6-Iodo-pyridin-3-yl)-7-aza-bicyclo[2.2....) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	25	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-3/beta-4 (Rat)	BDBM50049757 ((2R,4S)-2-(6-Iodo-pyridin-3-yl)-7-aza-bicyclo[2.2....) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	41	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1/M2/M3/M4/M5 (Rat)	BDBM50049757 ((2R,4S)-2-(6-Iodo-pyridin-3-yl)-7-aza-bicyclo[2.2....) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2 (Rat)	BDBM50049757 ((2R,4S)-2-(6-Iodo-pyridin-3-yl)-7-aza-bicyclo[2.2....) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	0.200	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2 (Rat)	BDBM50049757 ((2R,4S)-2-(6-Iodo-pyridin-3-yl)-7-aza-bicyclo[2.2....) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	0.200	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-2/beta-4 (Rat)	BDBM50049757 ((2R,4S)-2-(6-Iodo-pyridin-3-yl)-7-aza-bicyclo[2.2....) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	0.0800	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-3/beta-2 (Rat)	BDBM50049757 ((2R,4S)-2-(6-Iodo-pyridin-3-yl)-7-aza-bicyclo[2.2....) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	0.0300	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-3/beta-4 (Rat)	BDBM50049757 ((2R,4S)-2-(6-Iodo-pyridin-3-yl)-7-aza-bicyclo[2.2....) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-2/beta-2 (Rat)	BDBM50049757 ((2R,4S)-2-(6-Iodo-pyridin-3-yl)-7-aza-bicyclo[2.2....) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	0.0200	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2 (Rat)	BDBM50049757 ((2R,4S)-2-(6-Iodo-pyridin-3-yl)-7-aza-bicyclo[2.2....) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	0.0400	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-4 (Rat)	BDBM50049757 ((2R,4S)-2-(6-Iodo-pyridin-3-yl)-7-aza-bicyclo[2.2....) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	0.0900	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-3/beta-4 (Rat)	BDBM50049757 ((2R,4S)-2-(6-Iodo-pyridin-3-yl)-7-aza-bicyclo[2.2....) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	700	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-3/beta-4 (Human)	BDBM50049757 ((2R,4S)-2-(6-Iodo-pyridin-3-yl)-7-aza-bicyclo[2.2....) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	28	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Human)	BDBM50049757 ((2R,4S)-2-(6-Iodo-pyridin-3-yl)-7-aza-bicyclo[2.2....) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	6.30	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Human)	BDBM50049757 ((2R,4S)-2-(6-Iodo-pyridin-3-yl)-7-aza-bicyclo[2.2....) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Acetylcholine receptor subunit alpha (Human)	BDBM50049757 ((2R,4S)-2-(6-Iodo-pyridin-3-yl)-7-aza-bicyclo[2.2....) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Acetylcholine receptor subunit beta-like 2 (Fruit fly)	BDBM50049757 ((2R,4S)-2-(6-Iodo-pyridin-3-yl)-7-aza-bicyclo[2.2....) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	430	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4 (Mouse)	BDBM50049757 ((2R,4S)-2-(6-Iodo-pyridin-3-yl)-7-aza-bicyclo[2.2....) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.0370	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-3/beta-4 (Human)	BDBM50049757 ((2R,4S)-2-(6-Iodo-pyridin-3-yl)-7-aza-bicyclo[2.2....) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	19	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2 (Rat)	BDBM50049757 ((2R,4S)-2-(6-Iodo-pyridin-3-yl)-7-aza-bicyclo[2.2....) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	14	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-4 (Rat)	BDBM50049757 ((2R,4S)-2-(6-Iodo-pyridin-3-yl)-7-aza-bicyclo[2.2....) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	17	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-3/beta-4 (Rat)	BDBM50049757 ((2R,4S)-2-(6-Iodo-pyridin-3-yl)-7-aza-bicyclo[2.2....) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	128	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Human)	BDBM50049757 ((2R,4S)-2-(6-Iodo-pyridin-3-yl)-7-aza-bicyclo[2.2....) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.06	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2 (Rat)	BDBM50049757 ((2R,4S)-2-(6-Iodo-pyridin-3-yl)-7-aza-bicyclo[2.2....) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	0.0400	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-3/beta-4 (Human)	BDBM50049757 ((2R,4S)-2-(6-Iodo-pyridin-3-yl)-7-aza-bicyclo[2.2....) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-3/beta-2 (Human)	BDBM50049757 ((2R,4S)-2-(6-Iodo-pyridin-3-yl)-7-aza-bicyclo[2.2....) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	0.0300	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4 (Human)	BDBM50049757 ((2R,4S)-2-(6-Iodo-pyridin-3-yl)-7-aza-bicyclo[2.2....) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	120	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-3 (Human)	BDBM50049757 ((2R,4S)-2-(6-Iodo-pyridin-3-yl)-7-aza-bicyclo[2.2....) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	27	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-3/beta-4 (Rat)	BDBM50049757 ((2R,4S)-2-(6-Iodo-pyridin-3-yl)-7-aza-bicyclo[2.2....) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	16	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-3/beta-4 (Human)	BDBM50049757 ((2R,4S)-2-(6-Iodo-pyridin-3-yl)-7-aza-bicyclo[2.2....) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	7	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Rat)	BDBM50049757 ((2R,4S)-2-(6-Iodo-pyridin-3-yl)-7-aza-bicyclo[2.2....) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Acetylcholine receptor subunit alpha/beta/delta/gamma (Pacific electric ray)	BDBM50049757 ((2R,4S)-2-(6-Iodo-pyridin-3-yl)-7-aza-bicyclo[2.2....) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	200	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2 (Rat)	BDBM50049757 ((2R,4S)-2-(6-Iodo-pyridin-3-yl)-7-aza-bicyclo[2.2....) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	17	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Acetylcholine receptor subunit delta (Pacific electric ray)	BDBM50049757 ((2R,4S)-2-(6-Iodo-pyridin-3-yl)-7-aza-bicyclo[2.2....) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	100	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2 (Human)	BDBM50049757 ((2R,4S)-2-(6-Iodo-pyridin-3-yl)-7-aza-bicyclo[2.2....) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	17	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2 (Rat)	BDBM50049757 ((2R,4S)-2-(6-Iodo-pyridin-3-yl)-7-aza-bicyclo[2.2....) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	16	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Human)	BDBM50049757 ((2R,4S)-2-(6-Iodo-pyridin-3-yl)-7-aza-bicyclo[2.2....) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	3.50E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-3 (Human)	BDBM50049757 ((2R,4S)-2-(6-Iodo-pyridin-3-yl)-7-aza-bicyclo[2.2....) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	7	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2 (Human)	BDBM50049757 ((2R,4S)-2-(6-Iodo-pyridin-3-yl)-7-aza-bicyclo[2.2....) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	0.0200	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-3/beta-4 (Rat)	BDBM50049757 ((2R,4S)-2-(6-Iodo-pyridin-3-yl)-7-aza-bicyclo[2.2....) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	0.0370	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Acetylcholine receptor subunit alpha/beta/delta/gamma (Human)	BDBM50049757 ((2R,4S)-2-(6-Iodo-pyridin-3-yl)-7-aza-bicyclo[2.2....) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	0.0530	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2 (Human)	BDBM50049757 ((2R,4S)-2-(6-Iodo-pyridin-3-yl)-7-aza-bicyclo[2.2....) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	0.00880	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2 (Human)	BDBM50049757 ((2R,4S)-2-(6-Iodo-pyridin-3-yl)-7-aza-bicyclo[2.2....) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	27	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2 (Human)	BDBM50049757 ((2R,4S)-2-(6-Iodo-pyridin-3-yl)-7-aza-bicyclo[2.2....) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	50	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2 (Human)	BDBM50049757 ((2R,4S)-2-(6-Iodo-pyridin-3-yl)-7-aza-bicyclo[2.2....) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4 (Rat)	BDBM50049757 ((2R,4S)-2-(6-Iodo-pyridin-3-yl)-7-aza-bicyclo[2.2....) Show SMILES Show InChI	GoogleScholar	UniChem		0.00800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2 (Rat)	BDBM50049757 ((2R,4S)-2-(6-Iodo-pyridin-3-yl)-7-aza-bicyclo[2.2....) Show SMILES Show InChI	GoogleScholar	UniChem		0.00800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Nicotinic acetylcholine receptor (Cape York rat)	BDBM50049757 ((2R,4S)-2-(6-Iodo-pyridin-3-yl)-7-aza-bicyclo[2.2....) Show SMILES Show InChI	GoogleScholar	UniChem		0.00900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2 (Rat)	BDBM50049757 ((2R,4S)-2-(6-Iodo-pyridin-3-yl)-7-aza-bicyclo[2.2....) Show SMILES Show InChI	GoogleScholar	UniChem		0.00900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Acetylcholine receptor subunit alpha (Mouse)	BDBM50049757 ((2R,4S)-2-(6-Iodo-pyridin-3-yl)-7-aza-bicyclo[2.2....) Show SMILES Show InChI	GoogleScholar	UniChem		0.0100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair