BDBM50049774 5-(1a,2,3,7b-Tetrahydro-1H-cyclopropa[a]naphthalen-1-yl)-1H-imidazole::CHEMBL352645

SMILES C1Cc2ccccc2C2C1C2c1cnc[nH]1

InChI Key InChIKey=JRSOAPYTPOYVTE-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50049774   

TargetAromatase(Human)
UniversitäT De Saarlandes

Curated by ChEMBL
LigandPNGBDBM50049774(5-(1a,2,3,7b-Tetrahydro-1H-cyclopropa[a]naphthalen...)
Affinity DataIC50: 600nMAssay Description:In vitro inhibitory activity against Cytochrome P450 19A1 using human placental microsomes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
UniversitäT De Saarlandes

Curated by ChEMBL
LigandPNGBDBM50049774(5-(1a,2,3,7b-Tetrahydro-1H-cyclopropa[a]naphthalen...)
Affinity DataIC50: 9.00E+4nMAssay Description:In vitro inhibitory activity against Steroidgenic Cytochrome P450 17 alpha using rat testicular microsomes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Human)
UniversitäT De Saarlandes

Curated by ChEMBL
LigandPNGBDBM50049774(5-(1a,2,3,7b-Tetrahydro-1H-cyclopropa[a]naphthalen...)
Affinity DataIC50: 9.00E+4nMAssay Description:Inhibitory activity against Steroidgenic Cytochrome P450 C18 using Bovine adrenal mitochondria.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed