BDBM50049978 2-[(R)-1-{(S)-2-[(Azepane-1-carbonyl)-amino]-4-methyl-pentanoylamino}-2-(1H-indol-3-yl)-ethyl]-5-isopropyl-oxazole-4-carboxylic acid::CHEMBL171910

SMILES CC(C)C[C@H](NC(=O)N1CCCCCC1)C(=O)N[C@H](Cc1c[nH]c2ccccc12)c1nc(C(O)=O)c(o1)C(C)C

InChI Key InChIKey=GIFQSWPUGBKSPC-BJKOFHAPSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50049978   

TargetEndothelin-1 receptor(RAT)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50049978(2-[(R)-1-{(S)-2-[(Azepane-1-carbonyl)-amino]-4-met...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of Endothelin-1 binding to Endothelin A receptor binding sites in MMQ cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Sus scrofa)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50049978(2-[(R)-1-{(S)-2-[(Azepane-1-carbonyl)-amino]-4-met...)
Affinity DataIC50: >6.00E+4nMAssay Description:Inhibition of Endothelin-3(ET-3) binding to Endothelin B receptor binding sites in porcine cerebellar membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed