BDBM50050081 CHEMBL3317831::US9216988, 22

SMILES CC(C)CN(Cc1ccc(cc1)N1CCC(CC1)C(N)=O)S(=O)(=O)Cc1ccccc1

InChI Key InChIKey=IIEPXTQDMOYKTJ-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50050081   

TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50050081(CHEMBL3317831 | US9216988, 22)
Affinity DataEC50:  70nMAssay Description:Inverse agonist activity at N-terminal 6xHis-tagged human RORc ligand binding domain (241 to 486) expressed in bacterial expression system assessed a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50050081(CHEMBL3317831 | US9216988, 22)
Affinity DataIC50:  117nMpH: 7.4Assay Description:On day of the assay, 100 uL of 0.05% CHAPS (in deionized H2O) was added to all wells of the GFB Unifilter plate and allowed soak for 1 h. A wash bu...More data for this Ligand-Target Pair
In DepthDetails US Patent