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BDBM50050497 CHEMBL3181946

SMILES: Cc1cccc(c1)C(=O)Nc1cccc(NC(=O)c2ccc(cc2)C(C)(C)C)c1

InChI Key: InChIKey=CPVWLQBQDHUDMB-UHFFFAOYSA-N

Data: 2 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50050497   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Potassium channel subfamily K member 9


(Homo sapiens)
BDBM50050497
PNG
(CHEMBL3181946)
Show SMILES Cc1cccc(c1)C(=O)Nc1cccc(NC(=O)c2ccc(cc2)C(C)(C)C)c1
Show InChI InChI=1S/C25H26N2O2/c1-17-7-5-8-19(15-17)24(29)27-22-10-6-9-21(16-22)26-23(28)18-11-13-20(14-12-18)25(2,3)4/h5-16H,1-4H3,(H,26,28)(H,27,29)
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KEGG

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PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>3.00E+4n/an/an/an/an/an/a



University of Kansas Specialized Chemistry Center

Curated by ChEMBL


Assay Description
Inhibition of TASK-3 (unknown origin) expressed in CHO cells by thallium flux assay


Bioorg Med Chem Lett 24: 3968-73 (2014)

More data for this
Ligand-Target Pair
Potassium channel protein TASK-1


(Homo sapiens (Human))
BDBM50050497
PNG
(CHEMBL3181946)
Show SMILES Cc1cccc(c1)C(=O)Nc1cccc(NC(=O)c2ccc(cc2)C(C)(C)C)c1
Show InChI InChI=1S/C25H26N2O2/c1-17-7-5-8-19(15-17)24(29)27-22-10-6-9-21(16-22)26-23(28)18-11-13-20(14-12-18)25(2,3)4/h5-16H,1-4H3,(H,26,28)(H,27,29)
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 190n/an/an/an/an/an/a



University of Kansas Specialized Chemistry Center

Curated by ChEMBL


Assay Description
Inhibition of TASK-1 (unknown origin) expressed in CHO cells by thallium flux assay


Bioorg Med Chem Lett 24: 3968-73 (2014)

More data for this
Ligand-Target Pair