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BDBM50050747 CHEMBL296683::N-[(1R,2R)-2-(4-Hydroxy-phenyl)-indan-1-yl]-2,2-diphenyl-acetamide

SMILES: Oc1ccc(cc1)[C@H]1Cc2ccccc2[C@@H]1NC(=O)C(c1ccccc1)c1ccccc1

InChI Key: InChIKey=ZPORBGGQIAIHNC-IAPPQJPRSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50050747   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Sterol O-acyltransferase, Soat


(Rattus norvegicus)
BDBM50050747
PNG
(CHEMBL296683 | N-[(1R,2R)-2-(4-Hydroxy-phenyl)-ind...)
Show SMILES Oc1ccc(cc1)[C@H]1Cc2ccccc2[C@@H]1NC(=O)C(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C29H25NO2/c31-24-17-15-20(16-18-24)26-19-23-13-7-8-14-25(23)28(26)30-29(32)27(21-9-3-1-4-10-21)22-11-5-2-6-12-22/h1-18,26-28,31H,19H2,(H,30,32)/t26-,28+/m1/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 230n/an/an/an/an/an/a



Schering-Plough Research Institute

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against acyl-coenzyme A:cholesterol acyltransferase 1 from rat hepatic microsomes.


J Med Chem 39: 1704-19 (1996)


Article DOI: 10.1021/jm950833d
BindingDB Entry DOI: 10.7270/Q2QN65V7
More data for this
Ligand-Target Pair