BDBM50050797 2-(4,6-Dimethoxy-pyrimidin-2-yloxy)-3,3-bis-(4-fluoro-phenyl)-3-methoxy-propionic acid::CHEMBL304721

SMILES COc1cc(OC)nc(OC(C(O)=O)C(OC)(c2ccc(F)cc2)c2ccc(F)cc2)n1

InChI Key InChIKey=FTHTWZGSLVJZJB-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50050797   

TargetEndothelin-1 receptor(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50050797(2-(4,6-Dimethoxy-pyrimidin-2-yloxy)-3,3-bis-(4-flu...)
Affinity DataKi:  33nMAssay Description:Binding affinity of the compound towards human Endothelin A receptor by measuring its ability to displace [125I]-ET-1 from CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50050797(2-(4,6-Dimethoxy-pyrimidin-2-yloxy)-3,3-bis-(4-flu...)
Affinity DataKi:  970nMAssay Description:Binding affinity of the compound towards human Endothelin B receptor by measuring its ability to displace [125I]-ET-3 from guinea pig cerebellumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed