BDBM50050799 3,3-Bis-(4-chloro-phenyl)-2-(4,6-dimethoxy-pyrimidin-2-yloxy)-3-methoxy-propionic acid::CHEMBL64009

SMILES COc1cc(OC)nc(OC(C(O)=O)C(OC)(c2ccc(Cl)cc2)c2ccc(Cl)cc2)n1

InChI Key InChIKey=KYFGZGVSIVBTAB-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50050799   

TargetEndothelin-1 receptor(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50050799(3,3-Bis-(4-chloro-phenyl)-2-(4,6-dimethoxy-pyrimid...)
Affinity DataKi:  245nMAssay Description:Binding affinity of the compound towards human Endothelin A receptor by measuring its ability to displace [125I]-ET-1 from CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50050799(3,3-Bis-(4-chloro-phenyl)-2-(4,6-dimethoxy-pyrimid...)
Affinity DataKi:  1.30E+3nMAssay Description:Binding affinity of the compound towards human Endothelin B receptor by measuring its ability to displace [125I]-ET-3 from guinea pig cerebellumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed