BDBM50050913 CHEMBL286565::[2-(2,6-Dimethoxy-phenoxy)-ethyl]-((2R,3R)-3-p-tolyl-2,3-dihydro-benzo[1,4]dioxin-2-ylmethyl)-amine::[2-(2,6-Dimethoxy-phenoxy)-ethyl]-(3-p-tolyl-2,3-dihydro-benzo[1,4]dioxin-2-ylmethyl)-amine

SMILES COc1cccc(OC)c1OCCNC[C@H]1Oc2ccccc2O[C@@H]1c1ccc(C)cc1

InChI Key InChIKey=UNHGFWKSHHCRHF-UHFFFAOYSA-N

Data  7 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50050913   

TargetAlpha-1A adrenergic receptor(Bovine)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50050913([2-(2,6-Dimethoxy-phenoxy)-ethyl]-((2R,3R)-3-p-tol...)
Affinity DataKi:  8.34nMAssay Description:Binding affinity towards Alpha-1A adrenergic receptor in bovine brain using [3H]prazosin as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1A adrenergic receptor(Rat)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50050913([2-(2,6-Dimethoxy-phenoxy)-ethyl]-((2R,3R)-3-p-tol...)
Affinity DataKi:  40.3nMAssay Description:Binding affinity towards Alpha-1A adrenergic receptor in rat hippocampal membranes using [3H]prazosin as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1D adrenergic receptor(Rat)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50050913([2-(2,6-Dimethoxy-phenoxy)-ethyl]-((2R,3R)-3-p-tol...)
Affinity DataKi:  191nMAssay Description:Binding affinity towards Alpha-1D adrenergic receptor in rat brain using [3H]prazosin as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1B adrenergic receptor(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50050913([2-(2,6-Dimethoxy-phenoxy)-ethyl]-((2R,3R)-3-p-tol...)
Affinity DataKi:  195nMAssay Description:Binding affinity towards Alpha-1B adrenergic receptor hamster smooth muscle using [3H]prazosin as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1B adrenergic receptor(Rat)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50050913([2-(2,6-Dimethoxy-phenoxy)-ethyl]-((2R,3R)-3-p-tol...)
Affinity DataKi:  774nMAssay Description:Binding affinity towards Alpha-1B adrenergic receptor in rat liver using [3H]prazosin as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50050913([2-(2,6-Dimethoxy-phenoxy)-ethyl]-((2R,3R)-3-p-tol...)
Affinity DataKi:  827nMAssay Description:Binding affinity towards Dopamine receptor D2 in rat striatum using [3H]spiperone as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50050913([2-(2,6-Dimethoxy-phenoxy)-ethyl]-((2R,3R)-3-p-tol...)
Affinity DataKi:  1.26E+3nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1A receptor in rat hypocampus membrane using [3H]8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed