BDBM50051136 CHEMBL13740::{(R)-2,4,8-Trioxo-7-[(3,3,3-trifluoro-1-isopropyl-2-oxo-propylcarbamoyl)-methyl]-1,4,7,8-tetrahydro-2H-pyrido[3,4-d]pyrimidin-3-yl}-acetic acid benzyl ester

SMILES CC(C)C(NC(=O)Cn1ccc2c([nH]c(=O)n(CC(=O)OCc3ccccc3)c2=O)c1=O)C(=O)C(F)(F)F

InChI Key InChIKey=IMZGLRIYUYCKGL-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50051136   

TargetNeutrophil elastase(Homo sapiens (Human))
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50051136(CHEMBL13740 | {(R)-2,4,8-Trioxo-7-[(3,3,3-trifluor...)
Affinity DataKi:  44nMAssay Description:Inhibition of Human Neutrophil Elastase-catalyzed hydrolysis of the synthetic substrate MeO-Suc-Ala-Ala-Pro-Val-p- nitroanilide.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed