BDBM50051317 (3-Chloro-phenyl)-(5,6-dimethyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-amine::CHEMBL306081
SMILES Cc1[nH]c2ncnc(Nc3cccc(Cl)c3)c2c1C
InChI Key InChIKey=WXJDWBDGDSXEFA-UHFFFAOYSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50051317
Affinity DataIC50: 300nMAssay Description:Inhibition of EGF-stimulated tyrosine phosphorylation in A431 cells expressing EGF-RMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of Protein kinase C alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 27nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 4.05E+4nMAssay Description:Inhibition of tyrosine kinase v-AblMore data for this Ligand-Target Pair
Affinity DataIC50: 27nMAssay Description:In vitro inhibitory activity against epidermal growth factor receptorMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Ciba Pharmaceuticals
Curated by ChEMBL
Ciba Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of tyrosine kinase c-SrcMore data for this Ligand-Target Pair