BDBM50051358 2,3-Dihydroflavone::2,3-dihydro-2-phenyl-4H-1-benzopyran-4-one::2-phenyl-2,3-dihydro-4H-chromen-4-one::2-phenyl-4-chromanone::CHEMBL274318::Flavanone

SMILES O=C1CC(Oc2ccccc12)c1ccccc1

InChI Key InChIKey=ZONYXWQDUYMKFB-UHFFFAOYSA-N

Data  3 KI  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50051358   

TargetAdenosine receptor A3(Homo sapiens (Human))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50051358(2,3-Dihydroflavone | 2,3-dihydro-2-phenyl-4H-1-ben...)
Affinity DataKi:  1.62E+4nMAssay Description:Ability to displace [125I]-AB-MECA binding from adenosine A3 receptor.Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50051358(2,3-Dihydroflavone | 2,3-dihydro-2-phenyl-4H-1-ben...)
Affinity DataKi:  3.20E+4nMAssay Description:Binding affinity at Adenosine A1 receptor in rat brain membranes by [3H]-PIA displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50051358(2,3-Dihydroflavone | 2,3-dihydro-2-phenyl-4H-1-ben...)
Affinity DataKi:  5.01E+4nMAssay Description:Binding affinity against human adenosine A3 receptor in HEK293 cells using [125I]-AB-MECA 21680 radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50051358(2,3-Dihydroflavone | 2,3-dihydro-2-phenyl-4H-1-ben...)
Affinity DataIC50:  2.87E+3nMAssay Description:Inhibition of human recombinant MAOB expressed in BTI-TN-5B1-4 cells by para-tyramine oxidation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Upres Ea 4021 Biomol�Cules Et Th�Rapies Anti-Tumorales

Curated by ChEMBL
LigandPNGBDBM50051358(2,3-Dihydroflavone | 2,3-dihydro-2-phenyl-4H-1-ben...)
Affinity DataIC50:  2.80E+4nMAssay Description:Inhibition of human aromatase in placental microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Upres Ea 4021 Biomol�Cules Et Th�Rapies Anti-Tumorales

Curated by ChEMBL
LigandPNGBDBM50051358(2,3-Dihydroflavone | 2,3-dihydro-2-phenyl-4H-1-ben...)
Affinity DataIC50:  8.00E+3nMAssay Description:Inhibition of aromatase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Meijo University

Curated by ChEMBL
LigandPNGBDBM50051358(2,3-Dihydroflavone | 2,3-dihydro-2-phenyl-4H-1-ben...)
Affinity DataIC50:  2.00E+4nMAssay Description:Antagonist activity at androgen receptor in human MDA-kb2 cells assessed as inhibition of DHT-induced luciferase activity by luciferase reporter gene...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Rattus norvegicus (Rat))
University Of Basel

Curated by ChEMBL
LigandPNGBDBM50051358(2,3-Dihydroflavone | 2,3-dihydro-2-phenyl-4H-1-ben...)
Affinity DataIC50:  5.50E+4nMAssay Description:Inhibitory concentration against recombinant rat androgen receptor expressed in Escherichia coli using [3H]methyltrienolone (R 1881)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Upres Ea 4021 Biomol�Cules Et Th�Rapies Anti-Tumorales

Curated by ChEMBL
LigandPNGBDBM50051358(2,3-Dihydroflavone | 2,3-dihydro-2-phenyl-4H-1-ben...)
Affinity DataIC50:  2.85E+4nMAssay Description:In vitro inhibition of [1,2,6,7-3H]-androstenedione binding to human placental microsome cytochrome P450 19A1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Upres Ea 4021 Biomol�Cules Et Th�Rapies Anti-Tumorales

Curated by ChEMBL
LigandPNGBDBM50051358(2,3-Dihydroflavone | 2,3-dihydro-2-phenyl-4H-1-ben...)
Affinity DataIC50:  8.00E+3nMAssay Description:Inhibition of aromatase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed