BDBM50051818 CHEMBL3318333
SMILES Cc1ccc(cc1)-n1nnnc1C\C=N\Nc1ccc(Cl)cc1
InChI Key InChIKey=PPAOBOHNCAUWEH-WOJGMQOQSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50051818
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Swiss Institute Of Bioinformatics
Curated by ChEMBL
Swiss Institute Of Bioinformatics
Curated by ChEMBL
Affinity DataIC50: 3.10E+4nMAssay Description:Inhibition of IDO1 (unknown origin) using L-tryptophan substrate incubated for 60 mins in presence of 5 mM GSH by HPLCMore data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Swiss Institute Of Bioinformatics
Curated by ChEMBL
Swiss Institute Of Bioinformatics
Curated by ChEMBL
Affinity DataIC50: 5.40E+4nMAssay Description:Inhibition of IDO1 (unknown origin) using L-tryptophan substrate incubated for 60 mins by HPLCMore data for this Ligand-Target Pair
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of mouse TDO expressed in mouse P815B cells using L-tryptophan substrate incubated for 24 hrs by HPLC based cellular assayMore data for this Ligand-Target Pair
Affinity DataIC50: 340nMAssay Description:Inhibition of mouse IDO1 expressed in mouse P815B cells using L-tryptophan substrate incubated for 18 hrs by HPLC based cellular assayMore data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Swiss Institute Of Bioinformatics
Curated by ChEMBL
Swiss Institute Of Bioinformatics
Curated by ChEMBL
Affinity DataIC50: 5.30E+4nMAssay Description:Inhibition of IDO1 (unknown origin) using L-tryptophan substrate incubated for 60 mins in presence of 0.01% Triton-X by HPLCMore data for this Ligand-Target Pair