BDBM50051824 CHEMBL283208::[(S)-4-((R)-2-Amino-3-mercapto-propyl)-3-butyl-piperazin-1-yl]-(2,3-dimethyl-phenyl)-methanone

SMILES CCCC[C@H]1CN(CCN1C[C@@H](N)CS)C(=O)c1cccc(C)c1C

InChI Key InChIKey=IWQXXMWFEZGUPJ-MSOLQXFVSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50051824   

TargetDimer of Protein farnesyltransferase subunit beta(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50051824(CHEMBL283208 | [(S)-4-((R)-2-Amino-3-mercapto-prop...)
Affinity DataIC50:  5nMAssay Description:Inhibition of [3H]-FPP incorporation into Ha-Ras by FarnesyltransferaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50051824(CHEMBL283208 | [(S)-4-((R)-2-Amino-3-mercapto-prop...)
Affinity DataIC50:  360nMAssay Description:Inhibition of bovine Geranylgeranyl transferase type IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed