BDBM50052256 (S)-3-(amino(carboxy)methyl)bicyclo[1.1.1]pentane-1-carboxylic acid::3-((S)-Amino-carboxy-methyl)-bicyclo[1.1.1]pentane-1-carboxylic acid::3-(Amino-carboxy-methyl)-bicyclo[1.1.1]pentane-1-carboxylic acid(S-CBPG)::3-[amino(carboxy)methyl]bicyclo[1.1.1]pentane-1-carboxylic acid::CHEMBL43412
SMILES N[C@H](C(O)=O)C12CC(C1)(C2)C(O)=O
InChI Key InChIKey=KNSHLWJBSDBBRH-XOJFDHPMSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 21 hits for monomerid = 50052256
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
The Royal Danish School Of Pharmacy
Curated by ChEMBL
The Royal Danish School Of Pharmacy
Curated by ChEMBL
Affinity DataKi: 2.50E+4nMAssay Description:Agonist potency against cloned human metabotropic glutamate receptor 1More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
The Royal Danish School Of Pharmacy
Curated by ChEMBL
The Royal Danish School Of Pharmacy
Curated by ChEMBL
Affinity DataKi: 1.03E+5nMAssay Description:Agonist potency against cloned metabotropic glutamate receptor 5More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
The Royal Danish School Of Pharmacy
Curated by ChEMBL
The Royal Danish School Of Pharmacy
Curated by ChEMBL
Affinity DataKi: >3.00E+5nMAssay Description:Antagonist potency against cloned Metabotropic glutamate receptor 2More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
The Royal Danish School Of Pharmacy
Curated by ChEMBL
The Royal Danish School Of Pharmacy
Curated by ChEMBL
Affinity DataKi: >3.00E+5nMAssay Description:Agonist potency against cloned human Metabotropic glutamate receptor 4 (mGluR-4)More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
The Royal Danish School Of Pharmacy
Curated by ChEMBL
The Royal Danish School Of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 2.50E+4nMAssay Description:The compound was tested for inhibitory effect on second messenger formation in BHK cells expressing mGluR1aMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
The Royal Danish School Of Pharmacy
Curated by ChEMBL
The Royal Danish School Of Pharmacy
Curated by ChEMBL
Affinity DataIC50: >3.00E+5nMAssay Description:The compound was tested for inhibitory effect on second messenger formation in BHK cells expressing mGluR4aMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
The Royal Danish School Of Pharmacy
Curated by ChEMBL
The Royal Danish School Of Pharmacy
Curated by ChEMBL
Affinity DataEC50: >3.00E+5nMAssay Description:The compound was tested for effect on second messenger formation in BHK cells expressing mGluR4aMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
The Royal Danish School Of Pharmacy
Curated by ChEMBL
The Royal Danish School Of Pharmacy
Curated by ChEMBL
Affinity DataEC50: >3.00E+5nMAssay Description:The compound was tested for effect on second messenger formation in BHK cells expressing mGluR2More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
The Royal Danish School Of Pharmacy
Curated by ChEMBL
The Royal Danish School Of Pharmacy
Curated by ChEMBL
Affinity DataEC50: 1.03E+5nMAssay Description:The compound was tested for effect on second messenger formation in BHK cells expressing mGluR5a at half maximal concentrationMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
The Royal Danish School Of Pharmacy
Curated by ChEMBL
The Royal Danish School Of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibitory activity against mGluR1 receptorMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
The Royal Danish School Of Pharmacy
Curated by ChEMBL
The Royal Danish School Of Pharmacy
Curated by ChEMBL
Affinity DataEC50: 1.03E+5nMAssay Description:Concentration required to inhibit mGluR5a receptorMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
The Royal Danish School Of Pharmacy
Curated by ChEMBL
The Royal Danish School Of Pharmacy
Curated by ChEMBL
Affinity DataIC50: >3.00E+5nMAssay Description:Inhibitory activity of the compound against Metabotropic glutamate receptor 2 in the rat HEK 293 cells.More data for this Ligand-Target Pair
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibitory activity of the compound against Metabotropic glutamate receptor 1 in the rat LLC-PK1/HEK 293 cells.More data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+5nMAssay Description:Stimulation of [3H]phosphatidylinositol accumulation by rat Metabotropic glutamate receptor 4 co-expressed with Gqi9 protein in HEK 293 cells; Inacti...More data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+6nMAssay Description:Stimulation od [3H]phosphatidylinositol accumulation by rat Metabotropic glutamate receptor 4 co-expressed with Gqi9 protein in HEK 293 cellsMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
The Royal Danish School Of Pharmacy
Curated by ChEMBL
The Royal Danish School Of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 2.50E+4nMAssay Description:Antagonist activity at mGlu1 receptorMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
The Royal Danish School Of Pharmacy
Curated by ChEMBL
The Royal Danish School Of Pharmacy
Curated by ChEMBL
Affinity DataIC50: >3.00E+5nMAssay Description:The compound was tested for inhibitory effect on second messenger formation in BHK cells expressing mGluR5aMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
The Royal Danish School Of Pharmacy
Curated by ChEMBL
The Royal Danish School Of Pharmacy
Curated by ChEMBL
Affinity DataEC50: >3.00E+5nMAssay Description:The compound was tested for effect on second messenger formation in BHK cells expressing mGluR1aMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
The Royal Danish School Of Pharmacy
Curated by ChEMBL
The Royal Danish School Of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of mGluR1a receptorMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
The Royal Danish School Of Pharmacy
Curated by ChEMBL
The Royal Danish School Of Pharmacy
Curated by ChEMBL
Affinity DataEC50: >3.00E+5nMAssay Description:The compound was tested for effect on second messenger formation in BHK cells expressing mGluR5aMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
The Royal Danish School Of Pharmacy
Curated by ChEMBL
The Royal Danish School Of Pharmacy
Curated by ChEMBL
Affinity DataIC50: >3.00E+5nMAssay Description:The compound was tested for inhibitory effect on second messenger formation in BHK cells expressing mGluR2More data for this Ligand-Target Pair