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BDBM50052268 CHEMBL3318512

SMILES: Cc1ccc(CSC2=C(O)CC(CC2=O)c2ccccc2)cc1

InChI Key: InChIKey=RKBZJPCSUPCIEJ-UHFFFAOYNA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50052268   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Lactate dehydrogenase A (LDHA)


(Homo sapiens (Human))
BDBM50052268
PNG
(CHEMBL3318512)
Show SMILES Cc1ccc(CSC2=C(O)CC(CC2=O)c2ccccc2)cc1
Show InChI InChI=1/C20H20O2S/c1-14-7-9-15(10-8-14)13-23-20-18(21)11-17(12-19(20)22)16-5-3-2-4-6-16/h2-10,17,21H,11-13H2,1H3
PDB
MMDB

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Similars

Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Genentech

Curated by ChEMBL


Assay Description
Inhibition of human recombinant carboxy-terminal His-tagged LDHA by UV endpoint assay


Bioorg Med Chem Lett 24: 3764-71 (2014)


Article DOI: 10.1016/j.bmcl.2014.06.076
BindingDB Entry DOI: 10.7270/Q2445P46
More data for this
Ligand-Target Pair