BDBM50052276 (2S,3S)-3-(3,5-Bis-trifluoromethyl-benzyloxy)-1-(1H-imidazol-2-ylmethyl)-2-phenyl-piperidine::CHEMBL95626

SMILES FC(F)(F)c1cc(CO[C@H]2CCCN(Cc3ncc[nH]3)[C@H]2c2ccccc2)cc(c1)C(F)(F)F

InChI Key InChIKey=HBAPMWYWEYPKLS-UNMCSNQZSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50052276   

TargetSubstance-P receptor(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM50052276((2S,3S)-3-(3,5-Bis-trifluoromethyl-benzyloxy)-1-(1...)
Affinity DataIC50:  0.501nMAssay Description:Binding affinity was measured against the Tachykinin receptor 1 in CHO-expressed hNK1 using [125I]SP.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM50052276((2S,3S)-3-(3,5-Bis-trifluoromethyl-benzyloxy)-1-(1...)
Affinity DataIC50:  0.530nMAssay Description:Displacement of [125 I]-Tyr8 SP from the cloned human Tachykinin receptor 1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed