BDBM50053183 CHEMBL123481::Trifluoro-methanesulfonate1-[(E)-3-((2S,3S,5R)-2-carboxy-3-methyl-4,4,7-trioxo-4lambda*6*-thia-1-aza-bicyclo[3.2.0]hept-3-yl)-allyl]-pyridinium;
SMILES C[C@]1(\C=C\C[n+]2ccccc2)[C@@H](N2[C@@H](CC2=O)S1(=O)=O)C(O)=O
InChI Key InChIKey=HVPPRRYGCHMDTO-KXQICBMSSA-O
Data 13 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 13 hits for monomerid = 50053183
Affinity DataIC50: 1.50E+4nMAssay Description:Compound was tested for inhibition of Penicillin-binding protein 2 from Staphylococcus aureus (Schoch).More data for this Ligand-Target Pair
Affinity DataIC50: 8.10E+3nMAssay Description:Compound was tested for inhibition of 604 Cephalosporin resistant mutants of Penicillin-binding protein 2 from Streptococcus pneumoniaeMore data for this Ligand-Target Pair
Affinity DataIC50: 8.20E+3nMAssay Description:Compound was tested for inhibition of 503 Cephalosporin resistant mutants of Penicillin-binding protein 2 from Streptococcus pneumoniaeMore data for this Ligand-Target Pair
TargetPenicillin-binding protein, transpeptidase domain protein(Staphylococcus aureus)
F. Hoffmann-La Roche
Curated by ChEMBL
F. Hoffmann-La Roche
Curated by ChEMBL
Affinity DataIC50: >3.00E+5nMAssay Description:Compound was tested for inhibition of Penicillin-binding protein 3 from Escherichia coli.More data for this Ligand-Target Pair
Affinity DataIC50: 3.90E+3nMAssay Description:Compound was tested for inhibition of Penicillin-binding protein 2 from Streptococcus pneumoniaeMore data for this Ligand-Target Pair
TargetPenicillin-binding protein 1B(Escherichia coli (strain K12))
F. Hoffmann-La Roche
Curated by ChEMBL
F. Hoffmann-La Roche
Curated by ChEMBL
Affinity DataIC50: >1.00E+7nMAssay Description:Compound was tested for inhibition of Penicillin-binding protein 1b from Escherichia coli.More data for this Ligand-Target Pair
Affinity DataIC50: 7.50E+4nMAssay Description:Compound was tested for inhibition of Pseudomonas aeruginosa 18SH ,class C of Beta-lactamaseMore data for this Ligand-Target Pair
Affinity DataIC50: 1.80E+3nMAssay Description:Compound was tested for inhibition of Bacillus licheniformis 749/C ,class A of Beta-lactamaseMore data for this Ligand-Target Pair
Affinity DataIC50: 1.50E+4nMAssay Description:Compound was tested for inhibition of Penicillin-binding protein 4 from Staphylococcus aureus (Schoch).More data for this Ligand-Target Pair
TargetPenicillin-binding protein, transpeptidase domain protein(Staphylococcus aureus)
F. Hoffmann-La Roche
Curated by ChEMBL
F. Hoffmann-La Roche
Curated by ChEMBL
Affinity DataIC50: >3.00E+5nMAssay Description:Compound was tested for inhibition of Penicillin-binding protein 3 from Escherichia coli.More data for this Ligand-Target Pair
Affinity DataIC50: 1.60E+4nMAssay Description:Compound was tested for inhibition of Citrobacter freundii 1928, class C of Beta-lactamaseMore data for this Ligand-Target Pair
Affinity DataIC50: 3.30E+5nMAssay Description:Compound was tested for inhibition of Escherichia coli AmpC ,class C of Beta-lactamaseMore data for this Ligand-Target Pair
Affinity DataIC50: 3.90E+3nMAssay Description:Compound was tested for inhibition of Penicillin-binding protein 2 from Streptococcus pneumoniaeMore data for this Ligand-Target Pair