BDBM50053189 CHEMBL122384::{4-[5-Chloro-1-(4-fluoro-phenyl)-1H-indol-3-yl]-butyl}-dimethyl-amine

SMILES CN(C)CCCCc1cn(-c2ccc(F)cc2)c2ccc(Cl)cc12

InChI Key InChIKey=GNJLTBRLYYQCLP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50053189   

Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50053189(CHEMBL122384 | {4-[5-Chloro-1-(4-fluoro-phenyl)-1H...)
Affinity DataIC50:  100nMAssay Description:Binding affinity to serotonin 5-hydroxytryptamine 2A receptors using a radioligand [3H]-ketanserin binding assay in rat cortical membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50053189(CHEMBL122384 | {4-[5-Chloro-1-(4-fluoro-phenyl)-1H...)
Affinity DataIC50:  4.80E+3nMAssay Description:Binding affinity to dopamine receptor D2 using a [3H]-spiperone binding assay in rat cortical membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Rattus norvegicus (Rat))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50053189(CHEMBL122384 | {4-[5-Chloro-1-(4-fluoro-phenyl)-1H...)
Affinity DataIC50:  310nMAssay Description:Binding affinity to the alpha-1 adrenergic receptor using a radioligand [3H]-prazosin binding assay in rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed