BDBM50053519 7-[3-(3-Hydroxy-6,8-dioxa-bicyclo[3.2.1]oct-3-yl)-benzyloxy]-4-phenyl-3H-naphtho[2,3-c]furan-1-one::CHEMBL129253

SMILES OC1(CC2COC(C1)O2)c1cccc(COc2ccc3c(c4COC(=O)c4cc3c2)-c2ccccc2)c1

InChI Key InChIKey=ZDDCWWYSBQWYQR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50053519   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50053519(7-[3-(3-Hydroxy-6,8-dioxa-bicyclo[3.2.1]oct-3-yl)-...)
Affinity DataIC50:  240nMAssay Description:Potency to inhibit oxidation of arachidonic acid by recombinant human 5-lipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed