BDBM50053761 6-[1-Pyridazin-4-yl-1-(3-trifluoromethyl-phenyl)-meth-(E)-ylideneaminooxy]-hexanoic acid::CHEMBL336548

SMILES OC(=O)CCCCCO\N=C(\c1ccnnc1)c1cccc(c1)C(F)(F)F

InChI Key InChIKey=ATVVPDIARSXVPM-JJIBRWJFSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50053761   

TargetThromboxane-A synthase(Homo sapiens (Human))
University Of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50053761(6-[1-Pyridazin-4-yl-1-(3-trifluoromethyl-phenyl)-m...)
Affinity DataIC50:  693nMAssay Description:TXA2 synthetase inhibition measured by the inhibition of TXB2 formation by human gel-filtered platelets incubated with [14C]-arachidonic acidMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane A2 receptor(Homo sapiens (Human))
University Of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50053761(6-[1-Pyridazin-4-yl-1-(3-trifluoromethyl-phenyl)-m...)
Affinity DataIC50:  2.90E+4nMAssay Description:TXA2 receptor antagonism, measured by the displacement of [3H]SQ29,548 from the PGH-2/TXA-2 receptor on human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed