BDBM50054057 CHEMBL3319544

SMILES Nc1ccc(cn1)S(=O)(=O)N1CCN(CC1)c1ncc(cc1-c1ccccc1O)C(O)(C(F)(F)F)C(F)(F)F

InChI Key InChIKey=OGOGMCHKKXEGPD-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50054057   

TargetHexokinase-4(Mus musculus (Mouse))
Amgen

Curated by ChEMBL
LigandPNGBDBM50054057(CHEMBL3319544)
Affinity DataEC50:  565nMAssay Description:Induction of GK translocation from nucleus to cytoplasm of mouse hepatocytes preincubated for 20 mins followed by glucose challenge measured after 40...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50054057(CHEMBL3319544)
Affinity DataIC50:  6nMAssay Description:Inhibition of fluorescein-labeled human GK interaction with biotin-labeled human GKRP compound incubated for 20 mins prior to addition of fluorescein...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed