BDBM50054489 CHEMBL139656::N-((S)-3-Carbamimidoyl-2-hydroxy-cyclohexyl)-2-((R)-2-oxo-3-phenylmethanesulfonylamino-piperidin-1-yl)-acetamide

SMILES NC(=N)C1CCC[C@H](NC(=O)CN2CCC[C@@H](NS(=O)(=O)Cc3ccccc3)C2=O)C1O

InChI Key InChIKey=KXKMUXRHSOBPJF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50054489   

TargetProthrombin(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054489(N-((S)-3-Carbamimidoyl-2-hydroxy-cyclohexyl)-2-((R...)
Affinity DataIC50: 157nMAssay Description:In vitro for inhibition of serine protease thrombin(FIIa).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054489(N-((S)-3-Carbamimidoyl-2-hydroxy-cyclohexyl)-2-((R...)
Affinity DataIC50: 467nMAssay Description:In vitro for inhibition of serine protease Trypsin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054489(N-((S)-3-Carbamimidoyl-2-hydroxy-cyclohexyl)-2-((R...)
Affinity DataIC50: 2.50E+3nMAssay Description:In vitro for inhibition of Coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed