BDBM50054505 CHEMBL421760::N-(3-Carbamimidoyl-2-hydroxy-cyclohexyl)-2-((S)-2-oxo-3-phenylmethanesulfonylamino-pyrrolidin-1-yl)-acetamide

SMILES NC(=N)C1CCCC(NC(=O)CN2CC[C@H](NS(=O)(=O)Cc3ccccc3)C2=O)C1O

InChI Key InChIKey=BESVJPPKTOOXIB-HVEGKCCWSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50054505   

TargetProthrombin(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054505(CHEMBL421760 | N-(3-Carbamimidoyl-2-hydroxy-cycloh...)
Affinity DataIC50:  125nMAssay Description:compound was tested in vitro for inhibition of serine protease thrombin(FIIa).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054505(CHEMBL421760 | N-(3-Carbamimidoyl-2-hydroxy-cycloh...)
Affinity DataIC50:  2.50E+3nMAssay Description:compound was tested in vitro for inhibition of Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAnionic trypsin(Bos taurus)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054505(CHEMBL421760 | N-(3-Carbamimidoyl-2-hydroxy-cycloh...)
Affinity DataIC50:  538nMAssay Description:compound was tested in vitro for inhibition of serine protease Trypsin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed