BDBM50054510 2-Amino-6-methyl-5-phenylsulfanyl-3,7-dihydro-pyrrolo[2,3-d]pyrimidin-4-one::CHEMBL141869

SMILES Cc1[nH]c2nc(N)[nH]c(=O)c2c1Sc1ccccc1

InChI Key InChIKey=VWYPIOVWHNNYFB-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50054510   

TargetThymidylate synthase(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50054510(2-Amino-6-methyl-5-phenylsulfanyl-3,7-dihydro-pyrr...)
Affinity DataIC50:  3.00E+4nMAssay Description:The inhibitory concentration of compound was evaluated on Human Thymidylate synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50054510(2-Amino-6-methyl-5-phenylsulfanyl-3,7-dihydro-pyrr...)
Affinity DataIC50: >3.00E+4nMAssay Description:The inhibitory concentration of compound was evaluated on Lactobacillus casei Thymidylate synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50054510(2-Amino-6-methyl-5-phenylsulfanyl-3,7-dihydro-pyrr...)
Affinity DataIC50: >3.00E+4nMAssay Description:The inhibitory concentration of compound was evaluated on Streptococcus faecium Thymidylate synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50054510(2-Amino-6-methyl-5-phenylsulfanyl-3,7-dihydro-pyrr...)
Affinity DataIC50: >3.00E+4nMAssay Description:The inhibitory concentration of compound was evaluated on Escherichia coli Thymidylate synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50054510(2-Amino-6-methyl-5-phenylsulfanyl-3,7-dihydro-pyrr...)
Affinity DataIC50:  6.00E+4nMAssay Description:The inhibitory concentration of compound was evaluated on Pneumocystis carini Thymidylate synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed