BDBM50054512 2-Amino-5-(4-chloro-phenylsulfanyl)-6-methyl-3,7-dihydro-pyrrolo[2,3-d]pyrimidin-4-one::CHEMBL142176
SMILES Cc1[nH]c2nc(N)[nH]c(=O)c2c1Sc1ccc(Cl)cc1
InChI Key InChIKey=KXJWEXFVYFDHEI-UHFFFAOYSA-N
Data 8 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 50054512
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University
Curated by ChEMBL
Duquesne University
Curated by ChEMBL
Affinity DataIC50: 3.10E+3nMAssay Description:The inhibitory concentration of compound against Dihydrofolate reductases on Toxoplasma gondiiMore data for this Ligand-Target Pair
Affinity DataIC50: 5.30E+3nMAssay Description:The inhibitory concentration of compound was evaluated on Pneumocystis carini Thymidylate synthaseMore data for this Ligand-Target Pair
Affinity DataIC50: >2.60E+4nMAssay Description:The inhibitory concentration of compound was evaluated on Escherichia coli Thymidylate synthaseMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:The inhibitory concentration of compound was evaluated on Human Thymidylate synthaseMore data for this Ligand-Target Pair
Affinity DataIC50: >2.60E+3nMAssay Description:The inhibitory concentration of compound was evaluated on Lactobacillus casei Thymidylate synthaseMore data for this Ligand-Target Pair
Affinity DataIC50: 4.00E+4nMAssay Description:The inhibitory concentration of compound against Dihydrofolate reductases on Pneumocystis carini (pc)More data for this Ligand-Target Pair
Affinity DataIC50: 2.46E+4nMAssay Description:The inhibitory concentration of compound against Dihydrofolate reductases on rat liver (rl)More data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+4nMAssay Description:The inhibitory concentration of compound was evaluated on Streptococcus faecium Thymidylate synthaseMore data for this Ligand-Target Pair