BDBM50054552 (Z)-2-Cyano-3-cyclopropyl-3-hydroxy-N-(4-methylsulfanyl-phenyl)-acrylamide::CHEMBL143816

SMILES CSc1ccc(NC(=O)C(C#N)C(=O)C2CC2)cc1

InChI Key InChIKey=MOXHJPCGLKALOZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50054552   

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Rattus norvegicus (rat))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50054552((Z)-2-Cyano-3-cyclopropyl-3-hydroxy-N-(4-methylsul...)
Affinity DataIC50:  13nMAssay Description:Inhibitory concentration tested against enzyme dihydroorotate dehydrogenase in ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Mus musculus)
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50054552((Z)-2-Cyano-3-cyclopropyl-3-hydroxy-N-(4-methylsul...)
Affinity DataIC50:  445nMAssay Description:Inhibitory concentration tested on enzyme dihydroorotate dehydrogenase in mouseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed