BDBM50055014 7-(3,4-Dichloro-phenyl)-2,4,5,7-tetrahydro-3H-[1,3]diazepino[2,1-a]isoindol-7-ol::CHEMBL337510

SMILES OC1(N2CCCCN=C2c2ccccc12)c1ccc(Cl)c(Cl)c1

InChI Key InChIKey=JDGHEGQYEARKKK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50055014   

TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Drew University

Curated by ChEMBL
LigandPNGBDBM50055014(7-(3,4-Dichloro-phenyl)-2,4,5,7-tetrahydro-3H-[1,3...)
Affinity DataIC50:  0.260nMAssay Description:Inhibition of [3H]-dopamine uptake at the dopamine transporter in rat striatal tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Drew University

Curated by ChEMBL
LigandPNGBDBM50055014(7-(3,4-Dichloro-phenyl)-2,4,5,7-tetrahydro-3H-[1,3...)
Affinity DataIC50:  1.70nMAssay Description:Ability to displace [3H]-WIN-35,428 from dopamine transporter in rat caudate putamen tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Drew University

Curated by ChEMBL
LigandPNGBDBM50055014(7-(3,4-Dichloro-phenyl)-2,4,5,7-tetrahydro-3H-[1,3...)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of [3H]-WIN- 35,428 binding to the dopamine transporter in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed