BindingDB logo
myBDB logout

BDBM50055344 4-(3-Carbamoylmethyl-1-cyclohexylmethyl-2-methyl-1H-indol-5-yloxy)-butyric acid::CHEMBL146055

SMILES: Cc1c(CC(N)=O)c2cc(OCCCC(O)=O)ccc2n1CC1CCCCC1

InChI Key: InChIKey=AHHIMFVWOKPPRS-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50055344   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Phospholipase A2, membrane associated


(Homo sapiens (Human))
BDBM50055344
PNG
(4-(3-Carbamoylmethyl-1-cyclohexylmethyl-2-methyl-1...)
Show SMILES Cc1c(CC(N)=O)c2cc(OCCCC(O)=O)ccc2n1CC1CCCCC1
Show InChI InChI=1S/C22H30N2O4/c1-15-18(13-21(23)25)19-12-17(28-11-5-8-22(26)27)9-10-20(19)24(15)14-16-6-3-2-4-7-16/h9-10,12,16H,2-8,11,13-14H2,1H3,(H2,23,25)(H,26,27)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 654n/an/an/an/an/an/a



Eli Lilly and Company

Curated by ChEMBL


Assay Description
Inhibition of human non-pancreatic secretory phospholipase A2 (PLA2) in a chromogenic assay


J Med Chem 39: 5137-58 (1997)


Article DOI: 10.1021/jm960486n
BindingDB Entry DOI: 10.7270/Q2639NV0
More data for this
Ligand-Target Pair