BDBM50055689 12-(4-hydroxy-2-oxochromen-3-yl)-12H-5,10- dioxatetraphen-11-one (Compound 13)::7-(4-Hydroxy-2-oxo-2H-chromen-3-yl)-7H-chromeno[4,3-b]chromen-6-one::CHEMBL32926

SMILES Oc1c(C2c3ccccc3Oc3c2c(=O)oc2ccccc32)c(=O)oc2ccccc12

InChI Key InChIKey=OALUGYLIPAUKCN-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50055689   

TargetGag-Pol polyprotein [1148-1435](Human immunodeficiency virus type 1)
Nirma University

LigandPNGBDBM50055689(12-(4-hydroxy-2-oxochromen-3-yl)-12H-5,10- dioxate...)
Affinity DataIC50:  1.22E+5nMAssay Description:HIV-1 integrase inhibitory activity of compounds were determined using strand transferase inhibitory assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50055689(12-(4-hydroxy-2-oxochromen-3-yl)-12H-5,10- dioxate...)
Affinity DataIC50:  1.22E+5nMAssay Description:Integration of DNA by HIV -1 integraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50055689(12-(4-hydroxy-2-oxochromen-3-yl)-12H-5,10- dioxate...)
Affinity DataIC50:  1.27E+5nMAssay Description:Inhibitory activity against 3'-processing of DNA by HIV-1 integraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)TBA
LigandPNGBDBM50055689(12-(4-hydroxy-2-oxochromen-3-yl)-12H-5,10- dioxate...)
Affinity DataIC50:  8.32E+6nMAssay Description:Inhibition of Human immunodeficiency virus 1 integraseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetNAD(P)H dehydrogenase [quinone] 1(Homo sapiens (Human))
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM50055689(12-(4-hydroxy-2-oxochromen-3-yl)-12H-5,10- dioxate...)
Affinity DataIC50:  650nMAssay Description:Inhibition of human recombinant NQO1 in presence of BSAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50055689(12-(4-hydroxy-2-oxochromen-3-yl)-12H-5,10- dioxate...)
Affinity DataIC50:  1.63E+5nMAssay Description:Inhibitory activity of compound against integrase ; 122163More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD(P)H dehydrogenase [quinone] 1(Homo sapiens (Human))
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM50055689(12-(4-hydroxy-2-oxochromen-3-yl)-12H-5,10- dioxate...)
Affinity DataIC50:  200nMAssay Description:Inhibition of human recombinant NQO1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed