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BDBM50055723 3-[4-(4-Pyridin-2-yl-piperazin-1-ylmethyl)-cyclohexyl]-1H-indole::CHEMBL87504

SMILES: C([C@H]1CC[C@@H](CC1)c1c[nH]c2ccccc12)N1CCN(CC1)c1ccccn1

InChI Key: InChIKey=WYVYDCVFEZZZCK-MXVIHJGJSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50055723   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50055723
PNG
(3-[4-(4-Pyridin-2-yl-piperazin-1-ylmethyl)-cyclohe...)
Show SMILES C([C@H]1CC[C@@H](CC1)c1c[nH]c2ccccc12)N1CCN(CC1)c1ccccn1
Show InChI InChI=1S/C24H30N4/c1-2-6-23-21(5-1)22(17-26-23)20-10-8-19(9-11-20)18-27-13-15-28(16-14-27)24-7-3-4-12-25-24/h1-7,12,17,19-20,26H,8-11,13-16,18H2/t19-,20-
PDB

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Similars

Article
PubMed
85n/an/an/an/an/an/an/an/a



Division of Warner Lambert Company

Curated by ChEMBL


Assay Description
In vitro binding affinity for dopamine receptor D2 on rat striatal membranes by [3H]-spiperone displacement.


J Med Chem 40: 250-9 (1997)


Article DOI: 10.1021/jm960597m
BindingDB Entry DOI: 10.7270/Q28W3CD4
More data for this
Ligand-Target Pair