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BDBM50055754 (1-Benzyl-2-ethyl-5-methoxy-1H-indol-3-yl)-acetic acid hydrazide::CHEMBL149731

SMILES: CCc1c(CC(=O)NN)c2cc(OC)ccc2n1Cc1ccccc1

InChI Key: InChIKey=SSSAVGZSFZBVMQ-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50055754   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Phospholipase A2, membrane associated


(Homo sapiens (Human))
BDBM50055754
PNG
((1-Benzyl-2-ethyl-5-methoxy-1H-indol-3-yl)-acetic ...)
Show SMILES CCc1c(CC(=O)NN)c2cc(OC)ccc2n1Cc1ccccc1
Show InChI InChI=1S/C20H23N3O2/c1-3-18-17(12-20(24)22-21)16-11-15(25-2)9-10-19(16)23(18)13-14-7-5-4-6-8-14/h4-11H,3,12-13,21H2,1-2H3,(H,22,24)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 420n/an/an/an/an/an/a



Eli Lilly and Company

Curated by ChEMBL


Assay Description
Inhibition of Human Nonpancreatic Secretory Phospholipase A2 through Chromogenic assay


J Med Chem 39: 5119-36 (1997)


Article DOI: 10.1021/jm960485v
BindingDB Entry DOI: 10.7270/Q2542MQ5
More data for this
Ligand-Target Pair