BDBM50056004 CHEMBL3326667

SMILES Cc1nc(ccc1Oc1ncnc(OC2CCN(CC2)C(=O)OC2(C)CC2)c1F)S(C)(=O)=O

InChI Key InChIKey=TZEYAXGGRICVIJ-UHFFFAOYSA-N

Data  2 IC50  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50056004   

TargetGlucose-dependent insulinotropic receptor(Rattus norvegicus)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50056004(CHEMBL3326667)
Affinity DataEC50:  169nMAssay Description:Inhibition of rat GPR119 activity by homogeneous time resolved fluorescence cyclase (cAMP) assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50056004(CHEMBL3326667)
Affinity DataIC50:  2.57E+4nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Rattus norvegicus)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50056004(CHEMBL3326667)
Affinity DataEC50:  169nMAssay Description:Agonist activity at rat GPR119 by HTRF cAMP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50056004(CHEMBL3326667)
Affinity DataEC50:  14nMAssay Description:Inhibition of human GPR119 activity by homogeneous time resolved fluorescence cyclase (cAMP) assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50056004(CHEMBL3326667)
Affinity DataEC50:  14nMAssay Description:Agonist activity at human GPR119 by HTRF cAMP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50056004(CHEMBL3326667)
Affinity DataIC50:  2.34E+4nMAssay Description:Inhibition of CYP2C19 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed