BDBM50056029 CHEMBL316960::N-{2-[4-(2,3-Dihydro-benzo[1,4]dioxin-5-yl)-2,6-dimethyl-piperazin-1-yl]-ethyl}-4-fluoro-benzamide

SMILES CC1CN(CC(C)N1CCNC(=O)c1ccc(F)cc1)c1cccc2OCCOc12

InChI Key InChIKey=BRMLYAYOHYSGPN-UHFFFAOYSA-N

Data  1 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50056029   

Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Solvay Pharma

Curated by ChEMBL
LigandPNGBDBM50056029(CHEMBL316960 | N-{2-[4-(2,3-Dihydro-benzo[1,4]diox...)
Affinity DataKi:  1nMAssay Description:Binding affinity was evaluated by determining in vitro displacement of [3H]-8-OH-DPAT from the central 5-hydroxytryptamine 1A receptor recognition si...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Solvay Pharma

Curated by ChEMBL
LigandPNGBDBM50056029(CHEMBL316960 | N-{2-[4-(2,3-Dihydro-benzo[1,4]diox...)
Affinity DataEC50:  0.780nMAssay Description:In vitro potency at human 5-hydroxytryptamine 1A receptor in inhibiting forskolin-stimulated accumulation of intracellular cAMPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed