BDBM50056240 6-[(4-Methoxy-biphenyl-3-ylamino)-methyl]-5-methyl-pyrido[2,3-d]pyrimidine-2,4-diamine::CHEMBL357629

SMILES COc1ccc(cc1NCc1cnc2nc(N)nc(N)c2c1C)-c1ccccc1

InChI Key InChIKey=DTJIMLYSVZNISK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50056240   

TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50056240(6-[(4-Methoxy-biphenyl-3-ylamino)-methyl]-5-methyl...)
Affinity DataIC50:  640nMAssay Description:Inhibition of Dihydrofolate Reductase of Pneumocystis carinii.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50056240(6-[(4-Methoxy-biphenyl-3-ylamino)-methyl]-5-methyl...)
Affinity DataIC50:  68nMAssay Description:Inhibition of Dihydrofolate Reductase of Toxoplasma gondii.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50056240(6-[(4-Methoxy-biphenyl-3-ylamino)-methyl]-5-methyl...)
Affinity DataIC50:  440nMAssay Description:Inhibition of Dihydrofolate Reductase of Rat Liver.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed